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CVE-2024-50636

9.8 · CRITICAL

PyMOL 2.5.0 contains a vulnerability in its "Run Script" function, which allows the execution of arbitrary Python code embedded within .PYM files.

Published Nov 11, 2024CWE-94EPSS 1.25%

Overview

CVE-2024-50636 is a critical-severity vulnerability. It was published on November 11, 2024 and has a CVSS 3.1 base score of 9.8 (CRITICAL).

This vulnerability has a CVSS 3.1 base score of 9.8, rated CRITICAL. It can be exploited remotely over the network. No authentication or special privileges are required for exploitation.

Technical description

PyMOL 2.5.0 contains a vulnerability in its "Run Script" function, which allows the execution of arbitrary Python code embedded within .PYM files. Attackers can craft a malicious .PYM file containing a Python reverse shell payload and exploit the function to achieve Remote Command Execution (RCE). This vulnerability arises because PyMOL treats .PYM files as Python scripts without properly validating or restricting the commands within the script, enabling attackers to run unauthorized commands in the context of the user running the application.

Remediation

Check the references section for vendor advisories, patches, and mitigation guidance. If immediate patching is not possible, review the CVSS vector to understand the attack surface and apply compensating controls such as network segmentation or access restrictions.

References

GitHubgithub.com/schrodinger/pymol-open-source/issues/405GitHubgithub.com/yamerooo123/CVE/blob/main/CVE-2024-50636/Description.mdRefyoutu.be/SWnN_a1tUNc

How CyberStrike helps

Frequently asked questions

What is CVE-2024-50636?

CVE-2024-50636 is a critical-severity vulnerability. It was published on November 11, 2024 and has a CVSS 3.1 base score of 9.8 (CRITICAL).

How severe is CVE-2024-50636?

This vulnerability has a CVSS 3.1 base score of 9.8, rated CRITICAL. It can be exploited remotely over the network. No authentication or special privileges are required for exploitation.

How do I fix or remediate CVE-2024-50636?

Check the references section for vendor advisories, patches, and mitigation guidance. If immediate patching is not possible, review the CVSS vector to understand the attack surface and apply compensating controls such as network segmentation or access restrictions.

How can CyberStrike help with CVE-2024-50636?

CyberStrike is an open-source, AI-augmented pentesting engine. Rather than flag a version number, it tests whether an issue like CVE-2024-50636 is actually reachable in your own applications and APIs, then verifies each finding before reporting it. That tells you if the weakness is a real, exploitable risk in your environment or a false positive you can safely deprioritize.

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